Peppermint oil decreases the production of virulence-associated exoproteins by Staphylococcus aureus |
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| Authors: | Li Jing Dong Jing Qiu Jia-Zhang Wang Jian-Feng Luo Ming-Jing Li Hong-En Leng Bing-Feng Ren Wen-Zhi Deng Xu-Ming |
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| Affiliation: | Key Laboratory of Zoonosis, Ministry of Education, Institute of Zoonosis, College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. lijing5221@126.com |
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| Abstract: | The present study aimed to evaluate the antimicrobial activity of peppermint oil against Staphylococcus aureus, and further investigate the influence of peppermint oil on S. aureus virulence-related exoprotein production. The data show that peppermint oil, which contained high contents of menthone, isomenthone, neomenthol, menthol, and menthyl acetate, was active against S. aureus with minimal inhibitory concentrations (MICs) ranging from 64-256 μg/mL, and the production of S. aureus exotoxins was decreased by subinhibitory concentrations of peppermint oil in a dose-dependent manner. The findings suggest that peppermint oil may potentially be used to aid in the treatment of S. aureus infections. |
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