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Zinc oxide as an economical and efficient catalyst for the one-pot preparation of β-acetamido ketones via a four-component condensation reaction
Authors:Malek Taher Maghsoodlou  Asadollah Hassankhani  Sayyed Mostafa Habibi-Khorasani
Affiliation:a Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, PO Box 98135-674, Zahedan, Iran
b Department of Chemistry, Shahid Bahonar University of Kerman, Kerman 76169, Iran
Abstract:A new, efficient, one-pot, four-component condensation of benzaldehyde derivatives, acetophenone derivatives, acetyl chloride and acetonitrile in the presence of zinc oxide as catalyst is described for the synthesis of β-acetamido ketones.
Keywords:β-Acetamido ketone   Multicomponent synthesis   One-pot reaction   Zinc oxide   Catalyst
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