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Synthesis of chlorinated β- and γ-lactones from unsaturated acids with sodium hypochlorite and Lewis acids
Authors:José A López-López
Institution:Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Polígono Río San Pedro S/N, 11510 Puerto Real, Cádiz, Spain
Abstract:The direct synthesis of several β- and γ-lactones used as electrophilic sources of chlorine, sodium hypochlorite and a Lewis acid is described. The scope and limitations of the method are discussed.
Keywords:γ-Lactone  β-Lactone  Lactonization  Sodium hypochlorite  Lewis acid
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