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NbCl5-Catalyzed one-pot Mannich-type reaction: three component synthesis of β-amino carbonyl compounds
Authors:Rui Wang
Institution:Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China
Abstract:Three-component Mannich-type reaction of acetophenone, aromatic aldehydes and aromatic amines was catalyzed by NbCl5 at ambient temperature to give various β-amino ketones in high yields.
Keywords:NbCl5  Mannich-type reaction  β-Amino carbonyl compound  One-pot reaction
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