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Carteramine A, an inhibitor of neutrophil chemotaxis, from the marine sponge Stylissa carteri |
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| Authors: | Hirotsugu Kobayashi Koji Nagai Nobuhiro Fusetani Shigeki Matsunaga |
| Affiliation: | a Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan b Molecular Medicine Research Labs, Drug Discovery Research, Astellas Pharma Inc. 21, Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan c Fermentation Research Labs, Drug Discovery Research, Astellas Pharma Inc. 5-2-3, Toukoudai, Tsukuba, Ibaraki 305-2698, Japan d Institute for Systematics, and Ecology, University of Amsterdam, 1090 GT Amsterdam, The Netherlands |
| Abstract: | A new dimeric oroidin derivative, carteramine A (1), was isolated as a neutrophil chemotaxis inhibitor from the marine sponge Stylissa carteri. The structure of 1 was elucidated by the analysis of spectral data. |
| Keywords: | Sponge Neutrophil Chemotaxis Palau&rsquo amine Stylissa carteri |
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