Total synthesis of siomycin A |
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| Authors: | Tomonori Mori Taiji Goto Masaya Nakata |
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| Institution: | Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan |
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| Abstract: | We have succeeded in the total synthesis of siomycin A, a representative compound of the thiostrepton family of peptide antibiotics, featuring the one-pot cyclization-elongation of our strategic intermediates and the late-stage formations of the thiazoline and dehydroamino acid moieties. |
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| Keywords: | Siomycin A One-pot cyclization-elongation Thiazoline Dehydroamino acid |
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