A simple route to 6- and 7-fluoro-substituted naphthalene-1-carboxylic acids |
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| Authors: | Thomas M. Krü lle,Oscar Barba,Susan H. Davis,Graham Dawson,Martin J. Procter,Thomas Staroske,Gerard H. Thomas |
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| Affiliation: | Prosidion Limited,†Prosidion Limited is a subsidiary of OSI Pharmaceuticals, Inc.† Watlington Road, Oxford OX4 6LT, UK |
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| Abstract: | A simple one-pot method for the synthesis of 6-fluoro- and 6,7-difluoro-1-naphthoic acid is described. 6-Fluoro-1-naphthoic acid can be converted into 7-fluoro-1-naphthoic acid in three straightforward steps. |
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