Suzuki-Miyaura coupling of 2-bromopyridine with 2-formylphenylboronic acid |
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| Authors: | Fiona M McMillan David Reed |
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| Institution: | School of Chemistry, The University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, UK |
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| Abstract: | Suzuki-Miyaura coupling of 2-bromopyridine 1b with 2-formylphenylboronic acid 2 under standard conditions, gives 2-4-(2-pyridin-2-yl-benzyl)-pyridin-2-yl]benzoic acid 5b. A similar reaction is observed for 2-bromo-6-methylpyridine 1c. A mechanistic rationale for these unusual observations is suggested. |
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