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Fast and easy detection of aromatic amines on solid support
Authors:Steven E. Van der Plas
Affiliation:Department of Organic Chemistry, Ghent University, Krijgslaan 281, S4, B-9000 Gent, Belgium
Abstract:The use of p-nitrophenyl ester 1 has been shown to offer a reliable method for the detection of free aromatic amines. As little as 3.4 μmol g−1 of free aniline amino groups can be detected. The method has shown to be more sensitive for the detection of sterically hindered aromatic amines than the existing alternative based on reaction with chloranil.
Keywords:Solid phase synthesis   Colorimetric test   Aromatic amines   Disperse Red 1
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