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An efficient lactamization of fimbrolides to novel 1,5-dihydropyrrol-2-ones
Authors:Wai Kean Goh
Affiliation:School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia
Abstract:A new versatile method for the conversion of fimbrolides to the corresponding novel dihydropyrrol-2-ones is described. This new efficient lactamization protocol has the advantage of higher yields and can be used for the synthesis of a series of new dihydropyrrol-2-ones with interesting anti-bacterial properties.
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