Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives |
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Authors: | Hwan Myung Kim Pil Rye Yang Young-Gyu Ko Young Dae Chung Seung-Joon Jeon |
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Institution: | a Molecular Opto-Electronics Laboratory, Department of Chemistry, Korea University, 1-Anamdong, Seoul 136-701, Republic of Korea b Graduate School of Life Sciences and Biotechnology, Korea University, 1-Anamdong, Seoul 136-701, Republic of Korea |
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Abstract: | 2H-Benzoh]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule. |
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