Reversible folding-unfolding, aggregation protection, and multi-year stabilization, in high concentration protein solutions, using ionic liquids |
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| Authors: | Byrne Nolene Wang Li-Min Belieres Jean-Philippe Angell C Austen |
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| Institution: | Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA. |
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| Abstract: | We report the reversible thermal unfolding/refolding, and long period stabilization against aggregation and hydrolysis, of >200 mg ml(-1) solutions of lysozyme in ionic liquid-rich, ice-avoiding, solvents. |
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