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A highly efficient stereoselective synthesis of β-lactams |
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| Authors: | Sandeep Goyal Anang Pal Mangilal Chouhan Mukesh Gangar Sharad Sarak Vipin A Nair |
| Institution: | 1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, Mohali, Punjab 160062, India;2. Department of Pharmaceutical Sciences, Mohanlal Sukhadia University, Udaipur, Rajasthan 313001, India |
| Abstract: | An efficient strategy for a one-pot, single step synthesis of β-lactams employing an imidazolidinone based chiral auxiliary with various aldimines via asymmetric Mannich-type reaction has been described. |
| Keywords: | Chiral auxiliary Asymmetric Mannich-type reaction One-pot Stereoselectivity |
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