Direct C-H substitution reaction of anilides using hypervalent iodine and their regioselective issues |
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| Authors: | Kohki Yamamoto Shinichiro Kamino Daisuke Sawada |
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| Institution: | 1. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama-shi, Okayama 700-8530, Japan;2. Next-generation Imaging Team, RIKEN-CLST, Kobe-shi, Hyogo 650-0047, Japan |
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| Abstract: | The direct C-H substitution reactions of anilides using hypervalent iodine proceeded to afford azide, chloro, bromo, and fluoro derivatives, and their regioselectivity were described. In the specific reaction conditions, the unique regioisomers were obtained. |
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| Keywords: | Hypervalent iodine Anilide substitution Regioselective reaction |
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