Palladium-catalyzed synthesis of indole fused coumarins via cross-dehydrogenative coupling |
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Authors: | Amrita Dey Md Ashif Ali Sourav Jana Sadhanendu Samanta Alakananda Hajra |
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Affiliation: | Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India |
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Abstract: | The present method describes a palladium-catalyzed cross-dehydrogenative coupling reaction of coumarin and aniline for the synthesis of indole fused coumarin derivatives. The one-pot method is operationally simple and molecular oxygen is used as sole oxidant. The target compounds are obtained in good yields from commercially available precursors. |
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Keywords: | C-H activation Palladium Oxygen Coumarin Indole |
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