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Palladium-catalyzed synthesis of indole fused coumarins via cross-dehydrogenative coupling
Authors:Amrita Dey  Md Ashif Ali  Sourav Jana  Sadhanendu Samanta  Alakananda Hajra
Affiliation:Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
Abstract:The present method describes a palladium-catalyzed cross-dehydrogenative coupling reaction of coumarin and aniline for the synthesis of indole fused coumarin derivatives. The one-pot method is operationally simple and molecular oxygen is used as sole oxidant. The target compounds are obtained in good yields from commercially available precursors.
Keywords:C-H activation  Palladium  Oxygen  Coumarin  Indole
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