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Synthesis of trisaccharide-coated magnetic nanoparticles for antibody removal |
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| Authors: | Shuaihu Yan Cuixia Zhao Qidong Ren Xinni Xie Feng Yang Yuguo Du |
| Affiliation: | 1. State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;2. School of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, Beijing 100049, China;3. Wuhan Borenpharm Co., Ltd., Wuhan 430073, China |
| Abstract: | An efficient strategy for the synthesis of blood group A trisaccharide antigen has been developed. Magnetic nanoparticles having Fe3O4-Silica core-shell structure were prepared and functionalized with the prepared blood group A trisaccharide antigen derivative, and its excellent removal ability toward anti-A antibody was explored. |
| Keywords: | Blood group A Antigen Carbohydrate MNPs Glyco-NPs |
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