High efficient iron-catalyzed transfer hydrogenation of quinolines with Hantzsch ester as hydrogen source under mild conditions |
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| Authors: | Renke He Peng Cui Danwei Pi Yan Sun Haifeng Zhou |
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| Institution: | Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, China |
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| Abstract: | A highly efficient transfer hydrogenation of quinolines with Hantzsch ester as hydrogen source in the presence of 1 mol% Fe(OTf)2 under mild conditions has been developed. A series of substituted 1,2,3,4-tetrahydroquinoline derivatives were afforded in excellent yields with good functional group tolerance. |
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| Keywords: | Iron catalysis Transfer hydrogenation Quinolines Hantzsch ester |
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