A benzothizole-based fluorescent probe for Hg2+ recognition utilizing ESIPT coupled AIE characteristics |
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| Authors: | Dong Xu Lijun Tang Mingyu Tian Ping He Xiaomei Yan |
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| Institution: | 1. College of Chemistry and Chemical Engineering, Bohai University, Jinzhou 121013, China;2. College of Laboratory Medicine, Dalian Medical University, Dalian 116044, China |
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| Abstract: | A new benzothizole-based fluorescent probe 1 for Hg2+ recognition utilizing “ESIPT+AIE” strategy has been developed. In THF/H2O (1:1, v/v, PBS 20 mM, pH = 8.5) mixed solution, probe 1 displays rapid fluorescence responses to Hg2+ ions with high selectivity and sensitivity through Hg2+-triggered releasing of a compound possessing “ESIPT+AIE” characteristics. Cell imaging investigations indicate that probe 1 is cell permeable with low toxicity to MCF-7 cells, and applicable to detect Hg2+ ions in living MCF-7 cells. |
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| Keywords: | Dithioacetal ESIPT AIE Fluorescent probe Cell imaging |
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