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The preparation of astatine labelled tyrosine using an electrophilic reaction
Authors:Yu V Norseyev  D D Nhan  V A Khalkin  N Q Huan  L Vasaros
Institution:(1) Joint Institute for Nuclear Resarch, Dubna, USSR;(2) Central Research Institute for Physics, Budapest, Hungary
Abstract:Carrier-free astatotyrosine has been synthesized using an electrophilic reaction in acidic media. Temperature of 150–160°C and reaction time of 20–30 min were chosen as optimal conditions for the synthesis of astatotyrosine. Under the selected conditions the yield was about 90%.
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