The preparation of astatine labelled tyrosine using an electrophilic reaction |
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Authors: | Yu V Norseyev D D Nhan V A Khalkin N Q Huan L Vasaros |
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Institution: | (1) Joint Institute for Nuclear Resarch, Dubna, USSR;(2) Central Research Institute for Physics, Budapest, Hungary |
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Abstract: | Carrier-free astatotyrosine has been synthesized using an electrophilic reaction in acidic media. Temperature of 150–160°C and reaction time of 20–30 min were chosen as optimal conditions for the synthesis of astatotyrosine. Under the selected conditions the yield was about 90%. |
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