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Syntheses of Nucleoside Derivatives Containing Fmoc- or Trityl-protected Amino Acids |
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| Authors: | GUO Hui ZOU Wu-xin JI Qi MA Yu-xin MENG Ji-Ben |
| Institution: | Department of Chemistry, Nankai University, Tianjin 300071, P. R. China |
| Abstract: | Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids via N,N-dicyclohexyl-carbodiimide(DCC) mediated condensation are described. These reactions offer a mild and convenient method to synthesize aminoacylated nucleoside derivatives. |
| Keywords: | Nucleoside Amino acid Esterification |
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