Concise total synthesis of calothrixins A and B |
| |
| Authors: | Abe Takumi Ikeda Toshiaki Yanada Reiko Ishikura Minoru |
| |
| Affiliation: | Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan. |
| |
| Abstract: | The concise total synthesis of calothrixins A and B has been accomplished by utilizing the one-pot formation of hexatriene as a key intermediate via the palladium-catalyzed tandem cyclization/cross-coupling reaction of triethyl(indol-2-yl)borate. In another key transformation, the indolo[3,2-j]phenanthridine core was prepared in high yield via Cu(I)-mediated 6π-electrocyclization. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
