In situ quantitative measurement of concentration profiles in a microreactor with submicron resolution using multiplex CARS microscopy |
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| Authors: | Schafer Dawn Squier Jeff A van Maarseveen Jan Bonn Daniel Bonn Mischa Müller Michiel |
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| Affiliation: | Department of Physics, Colorado School of Mines, 1523 Illinois Street, Golden, Colorado 80401, USA. |
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| Abstract: | In situ quantitative imaging of concentration profiles of reactants and products inside a microfluidic reactor is achieved, with submicron spatial resolution with mM sensitivity and on ms time scales, for a given position. The label-free approach relies on quantitative vibrational spectroscopy, using Coherent Anti-Stokes Raman scattering microscopy in a spectrally resolved fashion, and is demonstrated on an elementary acid-base reaction. |
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