Shear-flow-induced unfolding of polymeric globules |
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Authors: | Alexander-Katz A Schneider M F Schneider S W Wixforth A Netz R R |
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Institution: | Physics Department, Technical University Munich, 85748 Garching, Germany. |
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Abstract: | The behavior of a single collapsed polymer under shear flow is examined using hydrodynamic simulations and scaling arguments. Below a threshold shear rate gamma.]{*}, the chain remains collapsed and only deforms slightly, while above gamma.]{*} the globule exhibits unfolding/refolding cycles. Hydrodynamics are crucial: In the free draining case, gamma.]{*} scales with the globule radius R as gamma.]{*} approximately R{-1}, while in the presence of hydrodynamic interactions gamma.]{*} approximately R. Experiments on the globular von Willebrand protein confirm the presence of an unfolding transition at a well-defined critical shear rate. |
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