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Acidic isomerization of alantolactone derivatives
Authors:S G Klochkov  S V Afanaséva  A N Pushin
Institution:(1) Institute of Physiologically Active Compounds, Russian Academy of Sciences, 142432 Moscow Region, Noginsk District, Chernogolovka, Severnyi proezd, 1
Abstract:A series of derivatives of the natural sesquiterpene lactones alantolactone (1) and isoalantolactone (2) was prepared. The α-methylene-γ-lactone moiety was retained in the structures of these for further modifications using reactions that affected exclusively the nonconjugated double bonds of the decalin ring. __________ Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 325–330, July–August, 2006.
Keywords:sesquiterpene lactones  alantolactone  isoalantolactone  acidic isomerization            Inula helenium L
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