Efficient Procedure for Preparing Salicyl Alcohols |
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| Authors: | Belyanin M L Filimonov V D Krasnov E A |
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| Institution: | (1) Siberian State Medical University, Tomsk, Russia;(2) Tomsk Polytechnic Institute, Tomsk, Russia |
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| Abstract: | A new convenient procedure was developed for selective ortho-hydroxymethylation of phenols by reaction of paraformaldehyde with a mixture of phenol and orthoboric acid. The method is general for phenols containing no strong electron-withdrawing substituents; it allows preparation of o-hydroxybenzyl alcohols of high purity in a high yield. |
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