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Three New Dammarane Glycosides from Gynostemma pentaphyllum
作者姓名:XinLIU  RongMinYU  WenLuanHSIAO  ShouXunZHAO  WenCaiYE
作者单位:[1]DepartmentofPhytochemistry,ChinaPharmaceuticalUniversity,Nanjing210009 [2]SchoolofPharmacy,JinanUniversity,Guangzhou510632 [3]DepartmentofBiology,TheHongKongUniversityofScienceandTechnology,HongKong
摘    要:Three new dammarane-type glycosides (1-3) had been isolated from the aerial part of Gynostemma pentaphyllum (Thunb) Makino. The structures of compounds 1-3 had been elucidated as 3β, 12β, 25-trihydroxy-20(S), 24(S)-epoxydammarane 3-O-β-D-glucopyranosyl (1→2)-β-D-xylo-pyranoside, 3β, 12β, 25-trihydroxy-20(S), 24(R)-epoxydammarane 3-O-β-D-glucopyranosyl(1→2)-β-D-xylopyranoside and 3β, 12β, 23β, 25-tetrahydroxy-20(S), 24(S)-epoxydammarane3-O-β-D-glucopyranosyl (1→2)-β-D-xylopyranoside, respectively, on the basis of chemical and spectro -scopic methods.

关 键 词:达玛烷  配糖  绞股蓝  分子结构

Three New Dammarane Glycosides from Gynostemma pentaphyllum
XinLIU RongMinYU WenLuanHSIAO ShouXunZHAO WenCaiYE.Three New Dammarane Glycosides from Gynostemma pentaphyllum[J].Chinese Chemical Letters,2004,15(1):46-48.
Authors:Xin LIU  Rong Min YU  Wen Luan HSIAO  Shou Xun ZHAO  Wen Cai YE
Institution:Xin LIU 1,Rong Min YU2,Wen Luan HSIAO 3,Shou Xun ZHAO 1,Wen Cai YE 1 * 1 Department of Phytochemistry,China Pharmaceutical University,Nanjing 210009 2 School of Pharmacy,Jinan University,Guangzhou 510632 3 Department of Biology,The Hong Kong University of Science and Technology,Hong Kong
Abstract:Three new dammarane-type glycosides (1-3) had been isolated from the aerial part of Gynostemma pentaphyllum (Thunb) Makino. The structures of compounds 1-3 had been elucidated as 3b, 12b, 25-trihydroxy-20(S), 24(S)-epoxydammarane 3-O-b-D-glucopyranosyl (12)-b-D- xylo -pyranoside, 3b, 12b, 25-trihydroxy-20(S), 24(R)-epoxydammarane 3-O-b-D-glucopyranosyl (12) -b-D-xylopyranoside and 3b, 12b, 23b, 25-tetrahydroxy-20(S), 24(S)-epoxydammarane 3-O-b-D- glucopyranosyl (12)-b-D-xylopyranoside, respectively, on the basis of chemical and spectro -scopic methods.
Keywords:Gynostemma pentaphyllum  dammarane-type glycoside  
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