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A Naphthalimide‐Based Fluorescence “Turn‐On” Probe for the Detection of Pb2+ in Aqueous Solution and Living Cells |
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| Authors: | Hio‐Ieng Un Chang‐Bo Huang Dr Junhai Huang Dr Chusen Huang Ti Jia Prof?Dr Lin Xu |
| Institution: | 1. Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai (China);2. Zhangjiang Institute, China State Institute of Pharmaceutical Industry, 1599 Zhangheng Road, Shanghai 201203 (P.R. China);3. Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234 (China) |
| Abstract: | An easily available naphthalimide‐based fluorescent probe NPA for Pb2+ detection was successfully developed. NPA exhibited an obvious fluorescence turn‐on response toward Pb2+ in aqueous solution and in living cells. Moreover, a series of model compounds were rationally designed and synthesized in order to explore the sensing mechanism and binding mode of NPA with Pb2+. |
| Keywords: | fluorescent probes lead ion naphthalimide photoinduced electron transfer sensors |