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Internal signal stochastic resonance of a synthetic gene network

Authors:	Zhiwei?Wang,Zhonghuai?Hou author-information" > author-information__contact u-icon-before" > mailto:hzhlj@ustc.edu.cn" title=" hzhlj@ustc.edu.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Houwen?Xin author-information" > author-information__contact u-icon-before" > mailto:nclxin@mail.ustc.edu.cn" title=" nclxin@mail.ustc.edu.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author

Affiliation:	Department of Chemical Physics, University of Science and Technology of China, Hefei 230026, China

Abstract:	The dynamics behavior of a synthetic gene network controlled by random noise is investigated using a model proposed recently. The phenomena of noise induced oscillation (NIO) of the protein concentrations and internal signal stochastic resonance (SR) are studied by com-puter simulation. We also find that there exists an optimal noise intensity that can most favor the occurrence of effective oscillation (EO). Finally we discuss the potential constructive roles of SR on gene expression systems.

Keywords:	noise noise-induced oscillation stochastic resonance gene expression synthetic gene network.
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