Synthesis of 3-pyridyl-substituted 5-amino-1,2,4-triazoles from aminoguanidine and pyridinecarboxylic acids |
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| Authors: | V. M. Chernyshev E. V. Tarasova A. V. Chernysheva V. A. Taranushich |
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| Affiliation: | 1.South-Russian State Technical University (Novocherkassk Polytechnic Institute),Novocherkassk, Rostov-on-Don oblast,Russia |
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| Abstract: | Effect of the molar ratio between reagents, temperature, and synthesis duration on the yield of 3-pyridylsubstituted 5-amino-1,2,4-triazoles in the reaction of aminoguanidine hydrochloride with pyridinecarboxylic acids under acid catalysis conditions was studied. A single-reactor method for synthesis of 3-pyridyl-substituted 5-amino-1,2,4-triazoles and their hydrochlorides was developed. |
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