首页 | 本学科首页   官方微博 | 高级检索  
     


Direct visualization of transient thermal response of a DNA origami
Authors:Song Jie  Arbona Jean-Michel  Zhang Zhao  Liu Lei  Xie Erqing  Elezgaray Juan  Aime Jean-Pierre  Gothelf Kurt Vesterager  Besenbacher Flemming  Dong Mingdong
Affiliation:Centre for DNA Nanotechnology at the Interdisciplinary Nanoscience Center, Aarhus University, DK-8000 Aarhus C, Denmark.
Abstract:The DNA origami approach enables the construction of complex objects from DNA strands. A fundamental understanding of the kinetics and thermodynamics of DNA origami assembly is extremely important for building large DNA structures with multifunctionality. Here both experimental and theoretical studies of DNA origami melting were carried out in order to reveal the reversible association/disassociation process. Furthermore, by careful control of the temperature cycling via in situ thermally controlled atomic force microscopy, the self-assembly process of a rectangular DNA origami tile was directly visualized, unveiling key mechanisms underlying their structural and thermodynamic features.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号