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Antitumour Activity of Chitosan Hydrogen Selenites
作者姓名:Cai Qin QIN  Ling XIAO  Yu Min DU*  Xiao Hai GAO
作者单位:Cai Qin QIN1,Ling XIAO1,Yu Min DU1*,Xiao Hai GAO2 1Department of Environmental Science,Wuhan University,Wuhan 430072 2Hubei Cancer Institute,Wuhan 430079
基金项目:This work was supported by the National Natural Science Foundation of China (grant No. 29977014) and China Capital Investment, Ltd., in Shanghai.
摘    要:Selenium is a biologically important element and essential for life1. Selenium deficiency causes severe degenerative disease, such as Kesan cardiomyopathy, and has been implicated in increasing the incidence of human cancer and some chronic ailment as well as ageing. Administration of selenium compounds such as sodium selenite protects animals against carcinogens and markedly reduces the incidence of various neoplasms in human2. Chitosan is one of the most abundant glycans in nature and its…


Antitumour Activity of Chitosan Hydrogen Selenites
Cai Qin QIN,Ling XIAO,Yu Min DU*,Xiao Hai GAO .Antitumour Activity of Chitosan Hydrogen Selenites[J].Chinese Chemical Letters,2002,13(3).
Authors:Cai Qin QIN  LING Xiao  Yu Min DU  Xiao Hai GAO
Abstract:Chitosans reacted with selenious acid to prepare chitosan hydrogen selenites, which were found to be growth-inhibitory against sarcoma 180 solid tumor. The results indicated that the activity also depended on the molecular weight of chitosan supports.
Keywords:Chitosan hydrogen selenites  antitumour activity  
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