Synthesis and reactions of 1-R-3-benzoyl-5-ethoxycarbonyl-6-oxo-1,2,3,6-tetrahydropyridine-2-thiones |
| |
| Authors: | V. N. Britsun A. N. Esipenko A. N. Chernega E. B. Rusanov M. O. Lozinskii |
| |
| Affiliation: | (1) Organic Chemistry Institute, National Academy of Sciences of Ukraine, Kiev, 02660 |
| |
| Abstract: | Cycloacylation of N-R-3-oxo-3-phenylpropanethioamides by diethyl ethoxymethylenemalonate occurs selectively to form 1-R-3-benzoyl-5-ethoxycarbonyl-6-oxo-1,2,3,6-tetrahydropyridine-2-thiones which are convenient starting materials for the synthesis of bi-and tricyclic hetero systems including the previously unknown 9-R-7-ethoxycarbonyl-5-phenyl-8,9-dihydropyrido[2,3-d][1,2,4]triazolo[1,5-a]-pyrimidin-8-ones. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1660–1669, November, 2007. |
| |
| Keywords: | 1-R-3-benzoyl-5-ethoxycarbonyl-6-oxo-1,2,3,6-tetrahydropyridine-2-thiones diethyl ethoxymethylenemalonate 6-ethoxycarbonyl-2-imino-8-methyl-4-phenyl-1,2,7,8-tetrahydropyrido[2,3-d]-pyrimidin-7-one 5-ethoxycarbonyl-7-methy-3-phenyl-6,7-dihydroisoxazolo[3,4-b]pyridine-6-one N-R-3-oxo-3-phenylpropanethioamides 9-R-7-ethoxycarbonyl-5-phenyl-8,9-dihydropyrido[2,3-d][1,2,4]triazolo-[1,5-a]pyrimidin-8-ones X-ray structural analysis cycloacylation |
| 本文献已被 SpringerLink 等数据库收录！ |
|
