Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles |
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| Authors: | Martín Rubén Larsen Catharine H Cuenca Ana Buchwald Stephen L |
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| Institution: | Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. |
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| Abstract: | A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles and heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors. |
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