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Synthesis of poison-frog alkaloids 237D, 207A, and two congeners of 235B' for evaluation to inhibitory effect of nicotinic acetylcholine receptors
Authors:Toyooka Naoki  Kawasaki Masashi  Nemoto Hideo
Affiliation:Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugatani, Toyama 930-0194, Japan. toyooka@ms.toyama-mpu.ac.jp
Abstract:Enantioselective synthesis of the poison-frog alkaloids 237D, 207A, and two congeners of 235B' has been achieved. The absolute stereochemistry of 237D was determined to be 5S, 8S, 9R by the present synthesis.
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