| Reaction of Ketene Dithioacetals with Pyrazolylcarbohydrazide： Synthesis and Biological Activities of Ethyl 5-Amino-1-（5＇-methyl-1 ＇-t-butyl-4＇-pyrazolyl）carbonyl-3-methylthio-1 H-pyrazole-4-carboxylate |
| |
| 引用本文： | 李明,文丽荣,付维军,赵桂龙,胡方中,杨华铮.Reaction of Ketene Dithioacetals with Pyrazolylcarbohydrazide： Synthesis and Biological Activities of Ethyl 5-Amino-1-（5＇-methyl-1 ＇-t-butyl-4＇-pyrazolyl）carbonyl-3-methylthio-1 H-pyrazole-4-carboxylate[J].中国化学,2004,22(9):1064-1066. |
| |
| 作者姓名： | 李明 文丽荣 付维军 赵桂龙 胡方中 杨华铮 |
| |
| 作者单位： | [1]CollegeofChemistryandMolecularEngineering,QingdaoUniversityofScienceandTechnology,Qingdao,Shandong266042,China [2]StateKeyLaboratoryofAppliedOrganicChemistry,LanzhouUniversity,Lanzhou，Gansu730000,China [3]StateKeyLaboratoryofElemento-organicChemistry,NankaiUniversity,Tianjin300071,China |
| |
| 摘 要： | The title compound, C16H23N5O3S, ethyl 5-amino-1-(5‘-methyl-1‘-t-butyl-4‘-pyrazolyl)carbonyl-3-methylthio-1H-pyrazole-4-carboxylate (5) has been synthesized by the treatment of ethyl 2-cyano-3,3-dimethylthioacrylate with 1-t-butyl-5-methyl-4-hydrazinocarbonylpyrazole (4) in refluxed ethanol. The possible mechanism of the above reaction was also discussed. The results of biological test show that the title compound has fungicidal and plant growth regulation activities.
|
| 关 键 词： | 合成 生物活性 乙基5-氨基-1-（5＇-甲基-1＇-t-丁基-4＇-吡唑基）羰基-3-甲基硫-1H-吡唑-4-羧酸盐 反应机理 |
Reaction of ketene dithioacetals with pyrazolylcarbohydrazide: Synthesis and biological activities of ethyl 5‐amino‐1–(5′‐methyl‐1′‐t‐butyl‐4′‐pyrazolyl)carbonyl‐3‐methylthio‐1 H‐pyrazole‐4‐carboxylate |
| |
| Ming Li,Li‐Rong Wen,Wei‐Jun Fu,Gui‐Long Zhao,Fang‐Zhong Hu,Hua‐Zheng Yang.Reaction of ketene dithioacetals with pyrazolylcarbohydrazide: Synthesis and biological activities of ethyl 5‐amino‐1–(5′‐methyl‐1′‐t‐butyl‐4′‐pyrazolyl)carbonyl‐3‐methylthio‐1 H‐pyrazole‐4‐carboxylate[J].Chinese Journal of Chemistry,2004,22(9):1064-1066. |
| |
| Authors: | Ming Li Li‐Rong Wen Wei‐Jun Fu Gui‐Long Zhao Fang‐Zhong Hu Hua‐Zheng Yang |
| |
| Abstract: | The title compound, C16H23N5O3S, ethyl 5‐amino‐l‐(5′‐methyl‐l'‐t‐butyl‐4′‐pyrazolyl)carbonyl‐3‐methylthio 1H‐pyrazole‐4‐carboxylate (5) has been synthesized by the treatment of ethyl 2‐cyano‐3,3‐dimethylthioacrylate with 1 ‐t‐butyl‐5‐methyl‐4‐hydrazinocarbonylpyrazole (4) in refluxed ethanol. The possible mechanism of the above reaction was also discussed. The results of biological test show that the title compound has fungicidal and plant growth regulation activities. |
| |
| Keywords: | pyrazole ethyl 2‐cyanc‐3 3‐dimethylthioacrylate reaction mechanism biological activity |
| 本文献已被 维普 等数据库收录！ |
