Heterocyclic variants of the 1,5-benzodiazepine system. VI. Derivatives of 2-methylthio-4-(p-r-phenyl)-3H-1,5-benzodiazepines |
| |
Authors: | Eduardo Corts Roberto Martínez Martha Ugalde Napolen Maldonado |
| |
Institution: | Eduardo Cortés,Roberto Martínez,Martha Ugalde,Napoleón Maldonado |
| |
Abstract: | Ethyl 3-3H-1,5-benzodiazepin-2-yl]carbazates II were prepared in moderate yields from the title compounds and ethyl carbazate. The compounds II were easily transformed into 1H-s-triazolo4,3-a]1,5]benzodiazepin-1-ones III via a one-step procedure. Reaction of triazolo-1,5-benzodiazepinones III with sodium hydride in methyl iodide gave a mixture of products from which were isolated two compounds IV and V . The structure of all products was confirmed by ir, 1H nmr and mass spectrometry. |
| |
Keywords: | |
|
|