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A novel and efficient synthesis of chiral C2-symmetric 1,4-diamines |
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| Authors: | Lianhong Xu |
| Institution: | Department of Medicinal Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA |
| Abstract: | A novel and efficient method for synthesis of (R,R)- and (S,S)-C2-symmetric 1,4-diamines was established. The key steps are a combination of Pinacol Coupling and Corey-Winter olefination. |
| Keywords: | C2-symmetric 1 4-diamines Corey-Winter olefination |
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