Divergent synthesis of isoindolo[2,1-a]indole and indolo[1,2-a]indole through copper-catalysed C- and N-arylations |
| |
| Authors: | Nekane Barbero Esther Domínguez |
| |
| Institution: | Kimika Organikoa II Saila, Zientzia eta Teknologia Facultatea, Euskal Herriko Unibertsitatea, PO Box 644, 48080 Bilbao, Spain |
| |
| Abstract: | A simple and efficient synthetic route to both isoindolo2,1-a]indole and its structural isomer indolo1,2-a]indole skeletons is presented. The key steps of the strategy are based on copper-catalysed Caryl-C and Caryl-N bond formation reactions, respectively. Moreover, we report the first copper-mediated intramolecular C-H functionalisation of an indole. |
| |
| Keywords: | Indoles Copper catalysts Arylation |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
