|
|||||
|
|
Total synthesis of verbalactone: an efficient, carbohydrate-based approach |
|
| Authors: | Ganesh B. Salunke Mukund K. Gurjar |
| Affiliation: | National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India |
| Abstract: | A carbohydrate-based strategy for the total synthesis of verbalactone has been described. (3R,5R)-3,5-dihydroxydecanoic acid was dimerised under Yamaguchi conditions to provide verbalactone in an overall yield of 17% starting from 3-deoxy-1,2:5,6-di-O-isopropylidine-α-d-glucofuranose. |
| Keywords: | Verbalactone smallcaps" >d-Glucose Chiral pool approach Yamaguchi&rsquo s macrolactonization |
| 本文献已被 ScienceDirect 等数据库收录！ | |