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A new strategy for the synthesis of aryl- and heteroaryl-substituted exocyclic olefins from allyl alcohols using PBr3
Authors:Shagufta
Affiliation:Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226001, UP, India
Abstract:Treatment of aryl and heteroaryl substituted allyl alcohols 7-14 with phosphorus tribromide at 0 °C furnished a new series of substituted exocyclic olefins 15-22 in good yields. The +I inductive effect of substituents on the aryl group is described.
Keywords:Aryl-substituted exocyclic olefin   Phosphorous tribromide   Allyl alcohol
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