A new strategy for the synthesis of aryl- and heteroaryl-substituted exocyclic olefins from allyl alcohols using PBr3 |
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Authors: | Shagufta |
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Affiliation: | Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226001, UP, India |
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Abstract: | Treatment of aryl and heteroaryl substituted allyl alcohols 7-14 with phosphorus tribromide at 0 °C furnished a new series of substituted exocyclic olefins 15-22 in good yields. The +I inductive effect of substituents on the aryl group is described. |
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Keywords: | Aryl-substituted exocyclic olefin Phosphorous tribromide Allyl alcohol |
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