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Measurement error in proportional hazards models for survival data with long-term survivors
Authors:Xiao-bing Zhao  Xian Zhou
Institution:1. School of Mathematics and Statistics, Zhejiang University of Finance and Economics, Hangzhou, 310018, China
2. Department of Applied Finance and Actuarial Studies, Macquarie University, North Ryde, Sydney, NSW, 2109, Australia
Abstract:This work studies a proportional hazards model for survival data with “long-term survivors”, in which covariates are subject to linear measurement error. It is well known that the naive estimators from both partial and full likelihood methods are inconsistent under this measurement error model. For measurement error models, methods of unbiased estimating function and corrected likelihood have been proposed in the literature. In this paper, we apply the corrected partial and full likelihood approaches to estimate the model and obtain statistical inference from survival data with long-term survivors. The asymptotic properties of the estimators are established. Simulation results illustrate that the proposed approaches provide useful tools for the models considered.
Keywords:proportional hazards  counting process  long-term survivor  measurement error  corrected score function
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