Combining two-directional synthesis and tandem reactions: a short formal synthesis of halichlorine |
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| Authors: | Gignoux Camille Newton Annabella F Barthelme Alexandre Lewis William Alcaraz Marie-Lyne Stockman Robert A |
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| Institution: | School of Chemistry, University of Nottingham, Nottingham, UK NG7 2RD. |
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| Abstract: | A short and efficient synthesis of an advanced intermediate (1) in the Clive route to halichlorine has been achieved in 12 steps and 13.2% yield by a combined two-directional synthesis/tandem reaction strategy. |
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