Synthesis, structure, and cytotoxicity of O-[3-(5-tetrazolyl)propyl]oximes |
| |
| Authors: | K Rubina E Abele S Belyakov I Shestakova Yu Popelis |
| |
| Institution: | (1) Latvian Institute of Organic Chemistry, Riga, LV-1006, Latvia |
| |
| Abstract: | A two-stage method was developed for the conversion of phenyl-and pyridylaldoximes and ketoximes into the corresponding O-3-(5-tetrazolyl)propyl]oximes. The structure of the sodium salt of 2-acetylpyridine O-3-(5-tetrazolyl)propyl]oxime was established X-ray diffraction analysis. This compound was shown to possess a high cytotoxic activity in vitro. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
