L-Proline catalyzed one-pot multi-component synthesis of 2-(1,3-diphenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one derivatives and their biological studies |
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作者姓名: | Hemal B. Mehta ;Bharat C. Dixit ;Ritu B. Dixit |
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作者单位: | a Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences, New Vallabh Vidyanagar 388121, India;
b Chemistry Departments, V. P. and R. P. T. P Science College, Affiliated to Sardar Patel University, Vallabh Vidyanagar 388120, India |
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摘 要: | A new series of quinazolin-4(3H)-one derivatives containing a(1 3-diphenyl-1H-pyrazol-4-yl) core with substituents at the 2-position and aromatic or heteroaromatic substituents at the 3-position were synthesized using an L-proline catalyzed one-pot multi-component reaction approach.All the synthesized compounds were characterized and screened for their antimicrobial,antifungal and anti-tubercular activities.
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关 键 词: | 多组分反应 酮衍生物 酸催化 二苯基 喹唑啉 合成 吡唑 生物学 |
收稿时间: | 11 September 2013 |
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