Amide as an efficient ligand in the palladium-catalyzed Suzuki coupling reaction in water/ethanol under aerobic conditions |
| |
| Authors: | Hai Yang Liu Kun Wang Hai Yan Fu Mao Lin Yuan Hua Chen Rui Xiang Li Key Lab of Green Chemistry Technology Ministry of Education the Institute of Homogeneous Catalysis College of Chemistry Sichuan University Chengdu China |
| |
| Institution: | Key Lab of Green Chemistry and Technology, Ministry of Education, the Institute of Homogeneous Catalysis, College of Chemistry, Sichuan University, Chengdu 610064, China |
| |
| Abstract: | Amide,which is derived from proline and is inexpensive and air-stable,has been synthesized and characterized by ~1H NMR,~(13)C NMR,and MS.It was found to be an efficient ligand in the palladium-catalyzed Suzuki cross-coupling reaction.In the Pd/amide catalytic system,aryl bromides can be coupled with phenylboronic acid in ethanol/water(1:2;v/v) in excellent yields even with a low Pd loading of 0.01 mol%.Moreover,the scope of the reaction is broad,and a wide variety of functional groups are tolerant. |
| |
| Keywords: | Suzuki cross-coupling Palladium catalyst Aryl bromides Amide Water |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国化学快报》浏览原始摘要信息 |
| 点击此处可从《中国化学快报》下载免费的PDF全文 |
|
