Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents |
| |
| Authors: | García-Cuadrado Domingo Barluenga Sofia Winssinger Nicolas |
| |
| Affiliation: | Institut de Science et d'Ingénierie Supramoléculaires, Université Louis Pasteur - 67000, Strasbourg, France. |
| |
| Abstract: | A concise sequence utilizing a Petasis three component reaction followed by a tandem aza-Cope-Mannich cyclization afforded novel polycyclic heterocycles in good yield; alternative iminium cyclization based on a Pictet-Spengler reaction or aminal formation led to divergent pathways affording skeletal diversity. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
