Practical and concise synthesis of 2-oxo-3,4,5,6-tetraethoxyazepane from D-glucono-1,5-lactone |
| |
| Authors: | Yan Jiao Zhi Jie Fang Yu Hua Jiang Bao Hui Zheng Jie Cheng |
| |
| Affiliation: | School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094, China |
| |
| Abstract: | 2-Oxo-3R,4S,5S,6S-tetraethoxyazepane was conveniently synthesized from D-glucono-1,5-lactone with a yield of 10% overall. The key step of synthetic route-reductive 1,6-cyclization was completed efficiently by using Ph_3P to give the expected lactam. |
| |
| Keywords: | Azepane Ph3P Reduction Iminosugars Glucono lactone |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国化学快报》浏览原始摘要信息 |
|
点击此处可从《中国化学快报》下载全文 |
|
