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Synthesis of N-Substituted Derivatives of (5-Amino-2-methyl-1H-indol-3-yl)acetic Acid
Authors:S A Maklakov  Yu I Smushkevich  I V Magedov
Institution:(1) Novomoskovsk Institute of the D. I. Mendeleev Russian University of Chemical Technology, Novomoskovsk, 301670;(2) D. I. Mendeleev Russian University of Chemical Technology, Moscow, 125047;(3) Moscow K. A. Timiryazev Agricultural Academy, Moscow, 127550, Russia
Abstract:A method has been developed for obtaining indole compounds containing an amino group in the benzene ring by the indolization of ethyl levulinate p-acetaminophenylhydrazone. A series of derivatives of (5-amino-2-methyl-1H-indol-3-yl)acetic acid at the 5-amino group has been synthesized.
Keywords:(5-amino-2-methyl-1H-indol-3-yl)acetic acid  N-(4-hydrazinophenyl)acetamide  indole  indomethacin  Fischer reaction
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