The Mukaiyama-Michael reaction of N-acyl-2,3-dihydro-4-pyridones: regio- and stereoselective synthesis of cis-2,6-disubstituted 1,2,5,6-tetrahydropyridines |
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| Authors: | Kuethe J T Comins D L |
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| Institution: | Department of Chemistry, North Carolina State University, Raleigh 27695-8204, USA. |
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| Abstract: | formula: see text] A convenient regio- and stereoselective preparation of 1,2,5,6-tetrahydropyridines of the type 1 has been developed, starting from readily available N-acyl-2,3-dihydro-4-pyridones 2. |
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