| The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine |
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| 作者姓名： | Yi Ming LIU Feng Xin WANG Sui Ping DENG Jian Ming OUYANG |
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| 作者单位： | Yi Ming LIU，Feng Xin WANG，Sui Ping DENG，Jian Ming OUYANG* Institute of Biomineralization and Lithiasis Research，Jinan University，Guangzhou 510632 |
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| 摘 要： | Kidney stone disease, which occurs in about 10% of the U.S. population, causes substantial suffering and occasional renal failure, yet the disease mechanism is poorly understood1. Kidney stones mostly contain microcrystals of calcium oxalate monohydrate (…
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| 关 键 词： | 草酸钙 柠檬酸钾 生物矿化 尿路结石 凝胶体 药物治疗 |
| 收稿时间： | 2005-11-23 |
The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine |
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| Yi Ming LIU Feng Xin WANG Sui Ping DENG Jian Ming OUYANG.The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine[J].Chinese Chemical Letters,2006,17(5):687-690. |
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| Authors: | Yi Ming LIU Feng Xin WANG Sui Ping DENG Jian Ming OUYANG |
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| Abstract: | The inducing effect of potassium citrate (K3cit) on simultaneous growth of calcium oxalate mono-(COM), di-(COD), and trihydrate (COT) crystals in synthetic urine was observed with double diffusion gelatinous technique. K3cit can induce the formation of COD and COT, inhibit the aggregation and decrease the surface area of COM crystals. It supported the clinical use of K3cit and may provide important clues to this disease in cure and in search for new drugs. |
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| Keywords: | Calcium oxalate potassium citrate biomineralization urinary stone gel |
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